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Albert Erives
Albert Erives (born March 4, 1972) is a biologist, who proposed the pacRNA model for the joint origin of the genetic code and universal homochirality. He is known for work at the intersection of genetics, evolution, developmental biology, and gene regulation. He has worked at the California Institute of Technology, University of California, Berkeley, and Dartmouth College, and is a professor at the University of Iowa.
== Molecular determinants of the genetic code ==
Inspired by results from Archaea genomics, Erives elaborated and described a specific stereochemical model of proto-anti-codon RNAs (pacRNAs).〔 The pacRNA model appears to predict the genetic code (i.e. the codon table) and biogenic amino acids. In addition, Erives uses the pacRNA model to show that the origin of the genetic code is related to another fundamental unsolved problems in biology: the evolutionary origins of universal homochirality. The model strongly implies that early RNA world was immediately an aminoacylated RNA world and that proteinogenic amino acids arose because of this intrinsic relation between nucleotides and a limited set of "biogenic" amino acids. The pacRNA model explicitly lists possible interactions between various anti-codon di-nucleotide and tri-nucleotide sequences and specific amino acids. When the nucleotides are D-ribose based, L-amino acids are preferred. The pacRNA model may also explain why extant tRNAs are heavily modified in all three domains of life.
Erives first presented the pacRNA model at NASAs 2012 Astrobiology Science Conference〔2012 Astrobiology Science Conference. url: http://abscicon2012.arc.nasa.gov/〕 and most recently at the 2013 Iowa City Darwin Day festival,〔2013 Iowa City Darwin Day. url: http://icdarwin.org〕 which focused on the origins of life on Earth.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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